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A century ago, mescaline
was the only chemical substance known to science that today would unequivocally
be called a psychedelic.
1960
Alexander Theodore Shulgin takes
mescaline and
awakens.
"It was
a day that will remain
blazingly vivid in my memory, and one which
unquestionably confirmed the
entire direction of my life." - Sasha
Sasha, deeply intrigued by
how a chemical could have such profound effects on thoughts, feelings and
perceptions, began to study these biomolecular effects.
"Dr. Shulgin had
something of a peekaboo relationship with the authorities.
He had a
strong relationship with the Drug Enforcement Administration; Bob Sager,
formerly head of the agency’s Western Laboratory, a close friend.
Dr. Shulgin often advised drug agents, served as an expert witness in
drug trials, wrote a reference work on controlled substances used by law
enforcement and for many years was licensed by the DEA to do research on
Schedule I drugs, those identified as having no clearly defined medical use and
a high potential for abuse." - Bruce Weber, June 7, 2014, New York
Times
1990 Shulgin publishes Pihkal: a
chemical love story – an abbreviation of ‘Phenethylamines I
have known and loved’ – blended personal history with detailed
procedures for making 179 psychoactive molecules.
Fellow psychonauts
eagerly test his recipes.
When the DEA finds copies of Pihkal in
clandestine drug labs, the agency revokes Shulgin’s licence to work on
Schedule 1
drugs.
"Sasha’s compounds are used in neurobiology to
investigate the role of serotonin receptors in the brain.
The chemicals
DOM (2,5-dimethoxy-4-methylamphetamine) and DOI
(2,5-dimethoxy-4-iodoamphetamine), for example, are used to activate particular
subtypes of serotonin receptors and study their relation to conditions like
depression and psychosis, including exploration of mechanisms of action of
antidepressant and antipsychotic medications.
DOI has been shown to
induce the rapid growth and reorganization of dendritic spines and synaptic
connections with other neurons, processes known to underlie what has come to be
referred to as neuroplasticity.
Today, in the early 21st century, there
are well over a hundred chemicals known to have psychedelic effects, some say
over 200.
The majority of these were discovered through chemical
synthesis and testing by one man: Sasha Shulgin." - David E. Presti
Neuroplasticity: The 10 Fundamentals Of Rewiring Your
Brain
"The
End of the World is
a projection of internal
catastrophe:
the paranoiac's subjective world
has come to an end since his
withdrawal of his passion for it.
And
the paranoiac builds it again, not
more splendid, it is true, but at least so that
he can once more live in
it.
He builds
it up by the work of his delusions.
The delusional formation,
which we take to be the pathological product, is in reality an attempt at
recovery, a process of reconstruction.
I remember having twice
been in danger of my life, and
each time the awareness
of the danger occurred to me quite suddenly.
On both occasions I
felt "this was the end," and while otherwise my inner language proceeded with
only indistinct sound images and slight lip movements, in these situations of
danger I heard the
words as if somebody was shouting them into my ear, and at the same time I saw
them as if they were printed on a piece of paper floating in the
air."
Sigmund
Freud
i
remember vividly feeling
compelled to action on the first trip through the looking glass
…
i could not identify the compeller but
it must have been the Holy
Spirit
…
all my behavior was basic
reality testing
…
i could
not discern whether the Holy Spirit was a good or a bad spirit
…
i will give you a personal account of one instant …
i took a handful of 8d box nails and set down on the sidewalk
…
i felt for magnetic field lines, identified them and started
aligning the nails …
i started with four nails and positioned them
in a compass pattern aligned with the magnetic lines …
i gently
rolled the nail toward the position in which it would be perfectly aligned with
the magnetic grid but released it slightly before it would hit the mark
…
i ended up with perfectly aligned radial pattern with eight rays
four nails deep, perfectly positioned in the center of a sidewalk square
…
8 radial arms at the compass directions and at the midpoint
between compass directions, 4 nails deep …
it took about a minute
…
my intent was to get the
nails to align in a perfectly symmetrical pattern and i used the
magnetic field lines of
the Earth to accomplish the task which i could actually feel with my hands
…
physical movement weds conceptualization of reality to physical
reality through ritual movement
creating Intentional Reality …
this is what would be considered a
miracle in ancient times …
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