Bisphenol A is first investigated in the search for synthetic estrogens.
Diethylstilbestrol, is determined to be more powerful than estrogen
itself, so bisphenol A is not used as a synthetic estrogen.
current uses are as a primary monomer in polycarbonate plastic and epoxy
Bisphenol A (BPA) is also used as an antioxidant in
plasticizers and as a polymerization inhibitor in PVC.
for the Evaluation of Risks to Human Reproduction is established within
the National Institutes of
Health to assess the dangers of chemicals to human reproductive health.
As with most government programs to study the effects of industry on
humans the bulk of the work is outsourced to
industry sponsored "think
2007 More than 100 government
studies confirmed the ability of BPA to mimic estrogen, cause genetic changes
that lead to prostate cancer, decreased testosterone, low sperm counts and
early female fertility.
A study of bisphenol A is done by Sciences
International funded by BASF,
ExxonMobil, 3-M, Union
Carbide, the National Association of Manufactures as well as numerous
other manufactures and industry groups.
reviews the scientific literature, writes the basic report, "suggests" who
should be a member of the scientific review panel, sets the parameters and the
agenda under which the panel operates.
Bisphenol A has not been
conclusively proven to have any detrimental effects on humans.
industry studies confirm.
Some polymers manufactured with bisphenol A are
FDA-approved for use as food additives.
and Drug Administration bisphenol A draft assessment of claims bisphenol A is safe, ignoring numerous independent and
government-funded studies which show risk of harm including brain and prostate
damage to developing infants, fetuses, and children, as well as increased risk
of diabetes and
FDA relies on two studies funded by
an arm of the American Chemistry Council, a trade organization
representing chemical manufacturers.
In test animals bisphenol A in
concentrations lower than those set by the EPA have caused permanent changes to
the genital tract, changes in breast tissue that predispose cells to hormones
and carcinogens, 30%
increase in prostate weight, signs of early puberty, decline in testicular
testosterone, breast cells predisposed to cancer, prostate cells more sensitive
to hormones and cancer, insulin résistance,
decreased maternal behavior, damage to eggs and chromosomes, hyperactivity and
reversal of normal sex difference in brain structure.
"Small amounts of
estrogenic oil, bisphenol A for example, can permanently disrupt cellular
control systems and predispose the prostate to disease in adulthood," said
Barry G. Timms, a professor of biomedical sciences at the University of South
Dakota who specializes in prostate biology.
"Exposure before birth to
bisphenol A and other estrogen mimics at low doses explains why we have this
increase in incidences of both breast and prostate cancers," said Patricia
Hunt, professor School of Molecular Biosciences at Washington State
"The failure to report the toxic effects of
bisphenol A in plastics follows a familiar pattern in which the industry
involved adamantly denies any harm despite overwhelming animal studies to the
Many neurodegenerative diseases, from
hyperactivity disorder to
brain tumors, are
dramatically rising in the Western culture, especially in children.
Many toxic substances are present in common foods, cleaners, clothes,
personal items and other household products, consumers and especially parents
would be well advised to become
aware and avoid exposure."
- Dennis Schumacher MD
"Reading the comments of Steve Hentges of the
Polycarbonate/BPA Global Group group gave me
a profound feeling of
Steve Hentges' denigration of scientific evidence of the
probable health dangers of bisphenol A echoed the comments, over years, of
"scientists" from the tobacco industry
findings of the health risks of tobacco.
One suspects that all the
evidence that is needed to prove the danger of BPA is in locked flies of the
plastics industry." - Norman Decker MD
"Researchers focused on 634 male workers at four
factories in China who were exposed to
elevated levels of BPA.
They followed the men over five years and
compared their sexual health with that of male workers in other Chinese
factories where BPA was not present.
The men handling BPA were four
times as likely to suffer from erectile dysfunction and seven
times as likely to have difficulty with ejaculation, said De-Kun Li, a
scientist at the Kaiser Foundation Research Institute, which conducted
the study with funds from the National Institute for Occupational Safety and
Health." - Lyndsey Layton, November 11, 2009
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