1987 Novartis AGNovartis
Beijing, founded by and Beijing Pharmaceutical group and Beijing
Zizhu Pharmaceuticals, is the first foreign pharmaceutical company in
Novartis AG Novartis Beijing founded by and Beijing
Pharmaceutical group and Beijing Zizhu Pharmaceuticals.
1989The Pfizer Dalian facility, built
jointly with Dalian Pharmaceuticals is the first to get certification in
Lilly returns to China.
1994 Merck set up its first
joint venture in China.
Bayer invests in
large-scale, world-class facilities in an integrated production site in the
Shanghai Chemical Industry Park.
Pharmaceutical Co., Ltd is founded as a joint-venture, with Shanghai
Pharmaceutical Industry Corporation and Shanghai Corporation of
Pharmaceutical Economic and Technical International
Eisai is the first manufacturer among the
US, European and Japanese pharmaceutical firms to manufacture in China via a
100% owned subsidiary.
Ingelheim enters Chinese market in and invested $25 million in a new
facility in Shanghai in 2002.
Hoechst Marion russell establisha
a head offices in Beijing to manage operations in mainland China and Hong Kong.
2000 There are 5,501 kidney transplants
performed in China, second only to the number in the US (13,372).
of immunosuppressant drugs are relatively high.
2001 AstraZeneca establishes its largest manufacturing
site in Asia in Wuxi.
Ingelheim enters invest $25 million in a new facility in
Anti-coagulant Novastan (argatroban) launched in
2004 Roche launches a medical
'education' campaign targeting 3,500 doctors in 20 Chinese cities.
November 19, 2008
The first foreign office of the
FDA opens in Beijing with
foreign funded pharmaceutical enterprises in China.
The top 20 pharmaceutical companies set up
joint ventures in China.
Market conditions are challenging with
competition at an
Pfizer produces and markets
more than 40 drugs in China.
Pfizer has manufacturing
facilities in Dalian, Suzhou and Wuxi.
GlaxoSmithKline has more than
2000 employees in China, and its drugs are sold in 60 cities.
sells drugs treating HIV, asthma and infection.
Merck sells antibiotics
prostate drugs, cardiovascular
drugs, pain relievers, osteoporosis and vaccines.
Novartis has four
manufacturing facilities in Beijing and Shanghai.
Novartis core businesses
involve patented drugs,
generic drugs, eye protection drugs
and health products.
German-French company, sells several drugs in China.
AstraZeneca has headquarters in
Shanghai, with 25 branch offices.
several products, including the
used in the management of schizophrenia and
Seroquel (quetiapine) and Nexium (esomeprazole).
AstraZeneca has nearly 3,000
employees working in manufacturing, sales,
and new product development.
AstraZeneca in over 110 targeted
cities, with 800
was one of the earliest to enter Chinese market.
Johnson & Johnson has established
subsidiaries which include Shanghai Johnson & Johnson Pharmaceuticals,
Ltd, Johnson & Johnson Medical (Shanghai) Ltd, Johnson &
Johnson Medical (China) Ltd, Johnson & Johnson (China) Ltd,
Johnson & Johnson (China) Investment Co., Ltd, manufacturing and
selling drugs in China.
Wyeth best-seller in China
the recognized leader in biotech, genomics and gene therapy.
Operations, in Hong Kong, Taiwan, and China are led by management
holding companies, with subgroups and production joint ventures operating
independently under the strategic direction of Bayer.
Bayer has production facilities
on stream in all corporately active business lines. Chinese production accounts
for an increasing proportion of profit margins.
Bayer is engaged
in a number of coöperation projects with some of the foremost research
institutes and universities in China, to conduct research in the field of
innovative materials, health care and crop
Bayer coöperates with the Chinese Academy of
Science and affiliated institutes such as the Institute of Materia
Medica and the Kunming Institute of Botany in Yunnan with the aim to
identify new compounds in the healthcare and crop science field.
Bayer supports a number of research chairs at Chinese
universities; Tsinghua-Bayer Public Health and HIV/AIDS Media Studies
Program, a national platform designed to play a key role in China's public
Bayer HealthCare supports a chair for Healthcare
Management at the China European International Business School (CEIBS) in
Its drugs treating
diseases and cardiovascular diseases are
established in Chinese pharmaceutical markets.
russell joint ventures; Hoechst Huabei Pharmaceuticals Ltd in
Shijiazhuang, a heartland of the Chinese pharmaceutical industry, and
Hoechst Shanghai International Pharmaceuticals Ltd.
Eli Lilly main
facility is in Suzhou, Jiangsu province and main products include cipro,
insulin, and erectile
Abbott Laboratories Ltd sells
a series of products including
ventures in China, Xian-Janssen Pharmaceutical's success includes a
range of high-volume medicines to treat gastronintestinal problems, fungi,
allergies and pain, as well as psychosis and
Janssen's decision to enter China
early, to invest inland, and to keep investment plans moving along in the wake
of 1989 Tiananmen Square event have helped build good relations with the
Chinese government. Paul Appermont and Joos Horsten lead the Xian-Janssen
Degussa is shifting a large
proportion of its pharmaceutical chemicals production to China to take
advantage of low-cost manufacturing.
Degussa restructure of
facilities, the vast majority in Germany, resulting in the transfer of the
manufacture of other products.
Rhodia is improving its
competitive position in analgesics by making a major investment in its Wuxi,
China acetaminophen (paracetamol) production facility and consolidating its
North American and European operations.
Rhodia shuttered its
Luling, Louisiana, paracetamol operations in 2004 and consolidated production
in Roussillon, France and Wuxi, China.
Paracetamol production capacity
is adjusted to match consumption levels.
Acetaminophen linked to autism?
Acetaminophen Linked to Lower Empathy Levels
Acetaminophen use in pregnancy linked to kids' behavioral
Mechanisms of Acetaminophen-Induced Liver Necrosis
11 Million Bottles Possibly Tainted With Metal
Sankyo is manufacturing the hyperlipemic
Mevalotin (pravastatin), anti-inflammatory Loxonin (loxoprofen),
antibiotic Banan (cephalosporin antibiotic) and hypertensive
Olmesartan (angiotensin II receptor antagonists).
is manufacturing and marketing all four global products - thiazolidinedione
with hypoglycemic action Actos (pioglitazone); anti-ulcer proton pump
inhibitor Takepron (lansoprazole); gonadotropin-releasing hormone
agonist cancer drug Leuplin (leuprolide acetate); and hypertensive
Yamanouchi is manufacturing and
marketing anti-ulcer histamine H2-receptor antagonist Gaster
(famotidine); urinary impediment treatment Harnal (tamsulosin); a
selective alpha blocker used in the symptomatic treatment of benign prostatic
hyperplasia and hypertensive calcium channel blocker Hypoca. There are
plans to launch Dolner for peripheral circulation and anti-emetic
Daiichi mainly sells synthetic antibacterials
Cravit (oral and injectable levofloxacin) and Tarivid
(ofloxacin). It originally planned to launch neurotransmission enhancer
Translon too, but after development was halted in Japan, development in
China also ended. Sales are behind plan chiefly due to the suspension of
Translon's development and the proliferation of generic and copycat
versions of Cravit.
Tanabe markets hypertensive
Herbesser(diltiazem hydrochloride) and Tanatril (imidapril
The China subsidiary Kuangchou Green Cross of
Mitsubishi Pharma has been extending transfusion business
(manufacturing, sales) since the days of the former Green Cross.
Mitsubishi Pharma sold its transfusion business in Japan to Otsuka
Pharmaceutical as part of a restructuring.
Prograf(tacrolimus or fujimycin) is being marketed in China by a
Fujisawa subsidiary - potential is significant due to the ever
increasing number of organ transplants.
The top 30 drugs by sales in
China (hospital market base) included two such drugs: Novartis'
immunosuppressant drug used in post-allogeneic organ transplantNeoral
(cyclosporine) and Roche's immunosuppressant drug used to prevent
rejection in organ transplantation CellCept (mycophenolate mofetil).
Chugai exports white blood cell production stimulant
Neutrogin (lenograstim) to China.
colony-stimulating factor is marketed in China.
its manufacturing and marketing operations in China and Asia earlier than in
the European and US markets.
Eisai sells two global products,
anti-ulcer proton pump inhibitors Pariet(rabeprazole) and Alzheimer's
acetylcholinesterase inhibitor treatment Aricept(donepezil), and adds
Kyowa Hakko has exported cancer
drugs and plans to market the hypertensive dihydropyridine calcium channel
blockerConiel(benidipine) and anti-allergy antihistamine and mast cell
stabilizer Allelock(olopatadine hydrochloride).
makes and sells health drinks (tonics) in China, but has no specific plans for
prescription medications. The rights to macrolide antibiotic
Clarith/Biaxin(clarithromycin) outside Japan are licensed to
Terumo is using China as a manufacturing base
making products for the US and European and Japanese markets. Terumo is
in the process of exploring China as a market.
McNeil Consumer Healthcare, a division of
Johnson & Johnson, announced
the recall of several hundred batches of popular over-the-counter medicines,
including Benadryl, Motrin, Rolaids, Simply Sleep, St. Joseph Aspirin and
The response was anything but swift.
The recall came 20
months after McNeil first began receiving consumer complaints about
moldy-smelling bottles of Tylenol Arthritis Relief caplets.
& Johnson did not conduct a timely, comprehensive investigation, did not
quickly identify the source of the problem, and did not notify authorities in a
timely fashion thus prolonging consumer exposure to the products.
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