Abraham Flexner on staff
at the Carnegie
Foundation, and funded by the
Foundation, 'sourced' the American 'medical' reformation following US
Congressional acceptance of the "Flexner
This infamous treatise exclusively benefited the IG Farben
pharmaceutical alliance that vilified every form of natural healing,
replacing nutrition with
petrochemicals to monopolize
In her 1993 book The Molecular Vision of Life, Dr. Lily
E. Kay, whom a 2001 MIT News Office obituary referred to as "one of the
outstanding historians of biology of her generation," argued that the "new
biology" was largely created by the Rockefeller Foundation and its subsidiary
program at the California Institute of Technology (Caltech) through a consensus
between a scientific elite and a business elite whose broader aims centered on
eugenics and the need to create a mechanism of social control and human
"The new science did not just evolve by natural selection
of randomly distributed disciplinary variants, nor did it ascend solely through
the compelling power of its ideas and its leaders. Rather, the rise of the new
biology was an expression of the
systematic cooperative efforts of America's scientific establishment -
scientists and their patrons - to direct
the study of animate phenomena
along selected paths toward a shared vision of science and society." - Dr. Lily
Practioners of alternative
healing methods consider the application of chemical toxins and surgeries to be
"The Allopathic approach to healing is a far cry
from Hippocratic method of healing which attempted to use natural methods of
"The term "allopathy" was invented by German
physician Samuel Hahnemann.
He conjoined allos "opposite" and pathos
"suffering" as a referent to harsh medical practices of his era which included
bleeding, purging, vomiting and
the administration of
highly toxic drugs.
These practices were
based on the ancient Greek humoral theory which attributed disease to an
imbalance of four humors (i.e., blood, phlegm,
and black and yellow bile) and four bodily
conditions (i.e, hot, cold, wet
and dry) that corresponded to four
air, fire, and water).
Physicians following the Hippocratic tradition attempted to balance the
humors by treating symptoms with "opposites." - William
Reliance on toxic chemical drugs is based
upon the philosophy of Santorio Santorio, also known as Sanctorius.
Santorio argued throughout his career that the fundamental properties
of human health were mathematical ones, such as number, position, and form -
breaking from describing the body and its functions in terms of Aristotelian
(and Galenic) elements and qualities.
This radical break with
traditional medical theory and natural philosophy proposed the
human body was a
machine the workings of which were determined by the shapes and positions
of its interlocking parts that could be broken down into constituent
Beginning from a fundamentally
unsound foundation Santorio made 'phenomenal' properties, seen from
a mechanistic Newtonian viewpoint,
central to his worldview
of nature and
While the central
metaphor of Aristotelian natural philosophy and Galenic medicine was organic,
Santorio made it mechanical: the
clock (more generally,
the machine) became the metaphor for
nature opening up a window for
While his 'trail and error' experiments were replicated and
augmented by his followers and finally surpassed by those of Antoine Lavoisier
he is still regarded by many as the father of
"How does a physician subscribing to "first do no harm" find himself or herself
prescribing either drugs that are inherently harmful or drugs at hazardous
levels? The answer is not complex. "Follow the money" is all one needs to
do." - Tom Pula
"The reason for encouraging independent studies of
clinical trials is that doing so can offer clues to risks and dangerous side
effects that begin to show up in significant numbers only after
the drug is on the market." -
very well today?
this exquisitely beautiful
pill is the 'solution'!
appropriate chemical combination!
1990 Americans spend $40 billion on
1998 JAMA study estimates 106,000
prescription medication deaths per year.
Americans spend $190 billion on
2006 Americans spend $280
billion on prescribed medications.
2009 Under new
the guidelines the FDA approves distribution of medical journal articles by
manufacturers that describe unapproved uses of their drugs.
2015 Americans spent $413 billion on prescribed
Over 1000% increase in twenty five
More than 10,000
drugs for sale in the pharmaceutical market.
Pushers spend ~ $1 billion to market a
estimated 80 percent of the active pharmaceutical ingredients used to make
drugs sold in America are imported, and
an estimated 40 percent of finished
drugs are made in foreign countries - much of both in
The physicians's accomplice,
undertaker's benefactor and grave worm's provider."
- Ambrose Bierce
Court ruling exempts generic drug manufactures from lawsuits
Karen Bartlett vs. Mutual Pharmaceutical Company 12-142
The US Chamber of Commerce and the
Pharmaceutical Research and Manufacturers of America ("PHRMA") argue
that exposing generic pharmaceutical manufacturers to
state law tort liability
will negatively impact the American healthcare system by denying physicians and
patients in some states access to certain generic medications.
Specifically, the US Chamber of Commerce and PHRMA contend that, since
generic pharmaceutical manufacturers distribute their products through a vast
and complex distribution system, it will be nearly impossible for generic drug
manufacturers to distribute certain drugs to only some states. Thus, the US
Chamber of Commerce and PHRMA allege that the difficulty of tailoring the
distribution of certain generic medications will encourage generic
pharmaceutical corporations to stop selling certain generic medications
Under the Supremacy Clause of the US Constitution, federal
laws represent the supreme law of the
land and may preempt or
override state laws.
The Hatch-Waxman Act allows generic drug
makers to bypass extensive testing requirements and enter the market if they
can prove that their generic drug is equivalent to an approved
brand-name drug and
carries the same labeling.
June 23, 2011 PLIVA,
Inc. v. Mensing, the Supreme Court
holds that the "sameness" requirement of the Hatch-Waxman Act
preempted state law
duties that had imposed stricter labeling requirements on generic drugs.
US Supreme Court ruled that
federal law related to pharmaceutical regulations preempts a person's ability
to sue in state courts and allege that a generic drug is poorly designed and
Justices cited the fact
that all generic drugs and their manufacturers, some 80% of all drugs consumed
in the US, are exempt from liability for side effects, mislabeling or virtually
any other negative reactions caused by their drugs.
In short, the Supreme
Court ruled that the FDA has authority over
pharmaceuticals in the US.
If the FDA says a drug is safe, that
takes precedent over actual facts, real
victims and any and all adverse reactions.
Drug manufacturers and
Wall Street investors celebrated.
One financial analyst pointed out, generic pharmaceutical corporation
profits should skyrocket.
Generic pharmaceutical corporations no longer
have to worry about safety or side effects, they are exempt from the
multi-million dollar court-imposed settlements awarded to victims of their
"Today's court decision provides a disincentive for
generic makers of drugs to monitor safety of their products and to make sure
that they have a surveillance system in place to detect adverse events that
pose a threat to patients." - Michael Carome, Public Citizen's Health Research
(Choose two or more of the above to comply with
If the FDA rules a drug is safe,
even if it
kills a loved one,
(or a loved
one kills you !)
you have no recourse !
"People are being forced to chose between being a
good employee or being a good family
member. That's not a choice
anyone should have to make." - Linda
Meric, director of 9 to 5, National Association of Working Women
"Sick days are typically unplanned, which results
in significant burdens to corporations when individuals do not show up as
expected." - Rick Chaifetz, CEO of
"When patients ask for a drug, they tend to get the
drug regardless of whether it is appropriate for them." - Joel Weissman, health
policy expert, Harvard Medical
"According to the 2005 Partnership Attitude
Tracking Study, 40% believe that prescription medicines are "much safer"
to use than illegal drugs. Furthermore, the same study concluded that 31%
wrong" with using prescription medicines without a prescription "once in
awhile." The truth of the matter is, these controlled substances are not
just highly dangerous, but they can prove lethal." - Joseph T. Rannazzisi, May 16,
Consumer minds are 'branded'.
understand how social control through prescribed petrochemical pharmaceuticals
works one must understand the human mind.
Human aspire for immortality,
to be elevated into a position outside of nature, where natural physical laws
are preempted and life continues eternally.
PHRMA uses this common
unnatural human desire and sells the idea of beating death with petrochemical
But many commonly prescribed petrochemical
pharmaceuticals have been shown to cause cancer !
therapy is among the most controversial medications in this
Industrially produced estrogen can promote uterine as well as
Many prescribed petrochemical pharmaceuticals have warnings
in their labels about cancer
Omeprazole (Prilosec©) causes abnormal cell growth and
stomach tumors (carcinoids) in rats.
Aldactone©) a blood pressure medicine, sometimes prescribed for hormonal
imbalances and facial hair growth in women, causes tumors in
Elidel© and Protopic©, are associated with lymmphoma and
arthritis injections Cimzia©, Enbrel©, Humira© and
Remicade©, expensive bio-tech drugs have been associated with lymphoma or
"In the New England Journal of Medicine, Sept. 25,
2008, investigators noted a higher incidence of cancer in subjects taking
Vytorin©." - Joe Graedon, pharmacologist & Teresa Graedon, doctorate
medical anthropology, nutrition expert
"Taking menopause hormones for
five years doubles the risk for
according to a new analysis of a federal study that reveals the most dramatic
evidence yet of the dangers of these popular pills." - Marilynn Marchione
"It is simply no longer possible to believe
much of the clinical research that is published, or to rely on the judgement of
trusted physicians or authoritative medical guidelines. I take no pleasure in
this conclusion, which I reached slowly and reluctantly over my two decades as
an editor of The New England Journal of Medicine." - Marcia Angell, MD,
"Drug Companies and Doctors: A story of Corruption" 1/15/09
"Just as a cake recipe requires you to use flour,
sugar and baking powder in the right amounts,
your brain needs a
fine chemical balance in order to perform at its best." - Web site text
advertising the antidepressant Paxil®
"In addition to questions of
FDA oversight, shouldn't we visit
the issue of direct pharmaceutical advertising to the consumer? That is
propaganda, not information."- Mary Jeanne Buttery MD
"The FDA allowing the
industry to spend billions of their customers' dollars stoking
inappropriate demand for their products by direct to consumer advertising and
trying to counteract this with the posting of difficult to
interpret information on obscure websites
is like hosing gasoline onto a fire with one hand and squirting it with a water
gun with the other." - Hyman J. Milstein MD
"Journalism awards consisting of cash prizes and
all-expense-paid trips given out by pharmaceutical corporations are among the
more "astonishing" financial ties between journalists and pharmaceutical
corporations." - Roni Caryn Rabin, November 21, 2008
"Pharmaceutical corporations work really hard
to get their message out to the public and physicians through advertisements
and continuing medical education and all the other things people hear about, so
it makes sense they would go after the media as well." - Dr. Steven Woloshin,
Dartmouth Institute for Health Policy Journalism 90% of pharmaceutical manufactures marketing budget goes to
selling physicians on the benefits of using drugs to deal with any and all
health problems the patient may be experiencing.
The rest goes to
advertising to the general public.
New England Journal of Medicine announces it will accept journalists who
accept money from drug companies because it is too difficult to find
journalists who have no ties.
Investigative journalists are referred to
a press liaison officer for
liaison officers refer the journalist to experts with favorable opinions
and to patients whose opinions have been carefully screened.
Embrace Award for reporting on urinary incontinence consists of trips to
Washington, DC, and Paris is offered by pharmaceutical firms
Eli Lilly and Boehringer
Television programming produced for doctors' waiting rooms
serve as a platform for pharmaceutical advertising and yet that television
programming is presented as journalism.
Bayer pleads guilty to violating
the federal Prescription Drug Marketing Act, paying $257 million
including a criminal
fine for its marketing of Cipro®.
2004Pfizer admits criminal
marketing of Neurontin® and signs a settlement stating it will no longer
market drugs for non-FDA approved uses and pays a fine of $430 million in
criminal fines and civil penalties.
18 US Senators and 62 US
Represenatives own stock in
offers doctors up to $1,000 a day to allow a Pfizer salesperson to spend time
with a physician according to a whistle-blower lawsuit filed by John
2005 Drug industry spending on
advertising has more than
doubled from $11.4 billion in 1996 to $29.9 billion.
Eli Lilly pleads guilty and pays $36
million for its illegal marketing of Evista® for
"It's an unbearable cost to a system that's going broke. The
Lilly cases involved the
illegal promotion of drugs that have been shown to cause substantial harm and
to patients." - Jerry Avorn, professor
2009 Pfizer settles for $2.3
billion with the government over off-label marketing for non-FDA
$1.3 billion criminal fine for kickbacks and
$1 billion is paid under the False Claims Act.
drugs involved are Bextra® (an anti-inflammatory drug), Geodon® (an
anti-psychotic drug), Lipitor® (a cholesterol drug), Norvasc®
(anti-hypertensive drug), Viagra® (erectile dysfunction), Zithromax®
(antibiotic), Zyrtec® (antihistamine), Zyvox® (an antibiotic),
Lyrica® (an anti-epileptic drug), Relpax® (anti-migraine drug), Celebrex®
(anti-inflammatory drug), and Depo-provera® (birth control).
"A way to cut health-care costs is to change the
way medicine is practiced. Most practitioners write expensive prescriptions
rather than address the real cause of most illness:
stress and unhealthy
life-style choices, not to mention poverty and lack of health care. Sometimes
the cheapest treatment (such as exercise, diet and relaxation) is the most
effective one." - Ellen Winer RN
"Doctors are taught that mistakes are unacceptable.
Medical mistakes are therefore viewed as a failure of character and any error
equals negligence. No one is taught what to do when medical errors do occur." -
Gary Null, PhD; Martin Feldman, MD; Debora Rasio, MD; Dorothy Smith, PhD;
"In the broader area of adverse drug reaction data,
the 250,000 reports received annually probably represent only 5% of the actual
reactions that occur." - Jerry Phillips, associate director FDA Office of Post
Marketing Drug Risk Assessment 2002 New England Journal of Medicine: one in four
patients suffer observable side effects from the over 3.34 billion
The drugs with the worst record of side effects
were selective serotonin reuptake
inhibitors (SSRIs), nonsteroidal anti-inflammatory drugs (NSAIDs), and
calcium-channel blockers (used to decrease blood pressure or
One-in-20 autopsies uncover problems that could have been
averted - saving the patients' lives - but were not, owing to misdiagnoses.
60 percent of physician errors are diagnostic.
50 percent of
misdiagnoses is deemed negligent.
Lawsuits for misdiagnoses are about
twice as common as for drug-related errors and result in the biggest payouts by
"The American medical
system is headed for multiple failures. The spiraling cost of healthcare is
well known: $7,100 per person this year, projected to increase to $12,000 in
2015 and compounding at more than double
the rate of inflation.
Medical care gobbles up one-sixth of the GDP.
Canada spends only 60% as
much per person on healthcare as America. Since 1980, the longevity of all
Canadians has improved more rapidly than that of white Americans, who typically
have the best health care. Britain spends only 40% as much as we do on
healthcare. According to the Journal of the American Medical
Association, middle-class insured Americans "are much less healthy than
their English counterparts".
Americans spend twice as much per person
on healthcare as the other 21 wealthiest countries and yet data from the World
Health Organization show that we live
the shortest amount of time in good health. America wasted more than $650
billion in 2005 on unnecessary and often harmful care. American and
international studies show that
the more a healthcare system relies on primary care, the better the outcomes
and the lower the cost. American medicine is heavy on
specialists and getting heavier. In just
the last eight years, the number of graduates of American medical schools
choosing careers in family practice and adult primary care has plummeted by
more than half.
Our healthcare system is
designed to maximize profits. US government now relies entirely on market
based, pro-business solutions to all social problems. No politician wants to be
tarred with the charge of promoting "socialized medicine." Even our nonprofit
medical instiutions shape the care they offer based on their own bottom lines
instead of the health needs of the communities they serve. The
Food and Drug Administration
is much better at protecting the interests of the drug and
medical-device industries than
those of patients." - John Abramson, clinical instructor, Harvard Medical
School, author of Overdosed America
|Generic Name (BRAND NAME)
||Date Withdrawn in US
| Tegaserod (ZELNORM)
|| March 2007
| Valdecoxib (BEXTRA)
|| April 2005
| Rofecoxib (VIOXX)
|| September 2004
| Cerivastatin (BAYCOL)
|| August 2001
| Cisapride (PROPULSID)
|| March 2000
| Troglitazone (REZULIN)
|| March 2000
| Grepafloxacin (RAXAR)
|| October 1999
| Bromfenac (DURACT)
|| June 1998
| Dexfenfluramine (REDUX)
|| September 1997
If you trust your doctor
in prescribing the right drugs for you, you might like to know that the
industry has started a new program to help bypass the caps on the price of
drugs sold in California related to workmen's compensation claims. If these
drugs are bought through a prescription then the price controls kick in but if
they are sold directly to the individual by the doctor then the price controls
do not apply. A doctor who prescribes a 90 tablet bottle of 800 milligram
ibuprofen can clear a profit of $65.50 on every bottle sold according to
DispenseXpress which buys drugs in
quantities and repackages them for sale through doctors.
If a doctor has a choice between
two medications to prescribe, has the opportunity to make a few bucks by
prescribing one and nothing by prescribing the other, which drug is he likely
to prescribe? After all it is all about cash flow!
"Pain is unavoidable. To be human is to be born
into pain." - Charles
Merck sold $2.5 billion
worth of Vioxx®(rofecoxib) in 2003. In December 2005 it was discovered that
the clinical trial of Vioxx®, conducted to gain approval by the FDA,
conveniently neglected to mention the three individuals who suffered
heart attacks during the
clinical trial. David Graham of the FDA Office of Drug Safety
stated that Vioxx® has caused as many as 140,000 cases of
heart disease and
killed up to 56,000 people.
"Merck's Vioxx® has killed 44,000 people
and injured 120,000 others. Only in America could you kill 44,000 and not go to
jail and get a raise." - Dr. Doug Henderson and Dr. Gary Null
which concluded that even low doses of Vioxx® increase the risk of
heart attack by 50% was
released 3 months late to allow
Merck to complete a
propaganda offense stating that even lower
doses of Vioxx® than those studied in the low dose study should be
been estimated conservatively that 16,500 NSAID-related
occur among patients with
arthritis or osteoarthritis every year in the US. This figure is similar to
the number of
from the acquired immunodeficiency syndrome and considerably greater than the
number of deaths from multiple myeloma,
asthma, cervical cancer,
or Hodgkin's disease." - J.S. Hochman, M.D., Executive Director of the National
Foundation for the Treatment of Pain 2003
anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with
analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever
More than 100,000 people are hospitalized each year
because of adverse reactions to NSAIDs.
More than 15,000 people die,
often because of compliciations caused by bleeding or perforated ulcers.
Drugs in this class include ibuprofen (Advil®, Motrin®),
diclofenac (Cataflam®, Voltaren®), meloxicam (Mobic®), naproxen
(Aleve®, Naprosyn®) and indomethacin (Indocin®). In addition to
digestive-tract damage, NSAIDs can raise blood pressure and increase the risk
of heart attack and stroke,
as well as injure kidneys and
The FDA has reports of diarrhea so severe, called ischemic
colitis, in users of the irritable-bowel treatment Zelnonn® that it caused
such complications as low blood pressure and fainting. The FDA has
received 20 reports of ischemic colitis, since Zelnonn® went on sale in
2002, fourteen patients were hospitalized, four died. The Food and Drug
Administration advised patients who experience new or worsened abdominal
pain or blood in their stools to stop taking the drug and call a
Research released in late 2005 shows that an individual that
uses the popular prescription heartburn drugs - Prilosec®, Prevacid®,
and Nexium® - are more prone to getting a potentially dangerously severe
diarrhea caused by clostridium difficile bacteria.
2006 the Journal of the American Medical association reported that the
use of Nexium®, Prilosec®, Prevacid®, Protinix® reduces calcium
absorption in the small intestine resulting in increased risk of hip fractures.
Long term users had 260% the average risk of hip fracture.
Chantix®Chantix® (varenicline) is a drug to help overcome addiction to
chemically engineered tobacco.
Varenicline is suspected in various
adverse drug event reports of causing a wide spectrum of injuries, including
serious accidents and falls, potentially lethal cardiac rhythm disturbances, severe
skin reactions, acute myocardial infarction, seizures,
psychosis, aggression and
suicide according to the FDA.
Pfizer produced a great example of stealth
advertising - a web site called MyTimeToQuit.com. The
advertisement has the look
and feel of a public service announcement, and mentions neither Pfizer, nor the
popular smoking cessation drug Chantix (varenicline). The
advertisement represents a
growing trend in drug advertising called "help-seeking ads," which don't
mention a drug by name, but instead address the condition the drug is meant to
treat, and then drive viewers to a toll-free 800 number or a web site that
offers an option to learn more about a
medication meant to treat the condition. This is a sneaky but legal way to
advertise drugs that bad side effects by not mentioning the drug by
name. The corporation is not required to
list bad side effects as it would in television
advertisement to comply with
The University of Wisconsin-Madison offers "a smoking
cessation course, funded by Pfizer, the maker of a smoking cessation drug; a
program on restless legs syndrome, funded by Boehringer Ingelheim, the maker of
a drug that treats the condition; and a course on premenstrual dysphoric
disorder, funded by Bayer HealthCare Pharmaceuticals."
has warned that the epilepsy drug
Zonegran® can cause a certain type of metabolic disorder that can increase
the risk of kidney
stones and bone
diseases. The FDA said doctors need to be
aware that treatment with
zonisamide can cause metabolic acidosis, a disturbance in the body's acid-base
balance that results in excessive acidity of the blood.
Viagra® & Cialis®!2008 Erectile dysfunction drug
manufacturers spend $237.2 million in 2007 and $313.4 million in 2008 marketing
Viagra® (Pfizer), Cialis® (Lilly) and Levitra® (GlaxoSmithKline).
warns consumers of True Man and Energy Max that "dietary supplements" marketed
as treatments for erectile dysfunction contain ingredients that can lower blood
pressure to dangerous levels in some users.
Protopic®- chance of contracting skin
cancer or lymphoma
Xenadrine EFX®FTC fines the makers of Xenadrine EFX®, One-A-Day
WeightSmart®, CortiSlim® and TrimSpa® $25 million in January 2007
for making false advertising
claims which included rapid weight loss, cancer prevention, reduction in risk
of osteoporosis and
Aprotinin® Aprotinin®, also called Trasylola, a heavily marketed still
Bayer drug, causes
sending an estimated 10,000 people a year to
kidney dialysis centers.
Aprotinin® also increases the risk of heart failure by 109% and stroke by
recombinant activated factor
VIIRecombinant Activated Factor VII® is an
experimental drug used on severely wounded soldiers in Iraq. It costs six
thousand per dose. Side effects include blood clots leading to
attacks and pulmonary embolisms.
"It's a completely irresponsible
and inappropriate use of a very, very drug." - Jawed Fareed director of
homostasis and thrombosis research at Loyola University Chicago and a
specialist in blood clotting and blood
Vytorin® and Zetia®
2007 Merck and Schering-Plough sells $5.2
billion of the anti-cholesterol drugs Vytorin® and Zetia®.
Vytorin®, which combines the cholesterol drug Zetia® with the
traditional statin drug simvastatin, was found to be no better than simvastatin
alone for reducing plaque buildup in the carotid arteries.
patients taking Vytorin® actually had slightly more plaque buildup during
the trial than those taking simvastatin alone. Merck and Schering-Plough completed
the ENHANCE study in 2005 but failed to announce the results.
announcement that the ENHANCE study failed to find any positive benefit from
the addition of Zetia® to a common, inexpensive, generic therapy raised
concerns that attempts were made to mask the minimal value of this new drug."-
Representative John Dingell, Committee on Energy and Commerce chairman 1/15/08
"In light of today's results, which were released nearly two years
after the ENHANCE trial ended, it is easy to conclude that Merck
intentionally sought to delay the release of this
data." - Representative Bart Stupak, chairs the oversight
"The pro-life, Michigan Democrat Bart Stupak led a small
but powerful bloc of Democratic lawmakers to oppose the bill because of its
language on federal funding of abortions. Stupak received a death threat.
Facing outside spending in his district and a vitriolic political climate, he
decided not to run for reelection. " - Chris Good, The Atlantic Mar 23,
calcium suppliments and hormone
therapyA massive federal study, the
$18-million Women's Health Initiative
published in the New England Journal
of Medicine, showed that calcium supplements made no significant difference
in woman's bone density and did not significantly reduce bone fractures.
Calcium plus vitamin D
supplementation and the risk of fractures
T. Poehlman built a reputation as one of the leading authorities on the
metabolic changes that come with aging, particularly during menopause; he
published more than 200 journal articles over two decades of research. Eric T.
Poehlman publish utterly fraudulent research alleging hormone replacement
injections as a therapy for menopause falsifying 17 grant applications to the
National Institutes of Health and fabricating data in 10 of his papers that
were submitted between 1992 and 2000. Eric T. Poehlman plead guilty to civil,
criminal and administrative charges.
An earlier Women's Health
Initiative study showed hormone treatment after menopause conferred more
risks than benefits.
2007 State court jury in
Philadelphia found Wyeth "malicious, wanton, willful or oppressive" in the
manufacturing, marketing and sales of Prempro menopause pill. Mary Daniel,
after using the hormone therapy pill, contracted breast
Wyeth paid ghostwriters
to produce medical journal articles favorable to its female hormone replacement
therapy Prempro®. As early as 1997, Wyeth paid the medical writing firm
DesignWrite to publish favorable journal articles about Prempro® under
Around 5000 lawsuits wait to be heard over the hormone
therapies Prempro® and Premarin®.
"Newly unveiled court
documents show that ghostwriters paid by a pharmaceutical corporation played a
major role in producing 26 scientific papers backing the use of hormone
replacement therapy in women. The articles, published in medical journals
between 1998 and 2005, emphasized the benefits and de-emphasized the risks of
taking hormones" - Natasha Singer, August 4, 2009
The Council on
Hormone Education sponsors a University of Wisconsin-Madison online course
entirely funded by a $12 million grant from Wyeth Pharmaceuticals. Thirty-four
of the 40 Council on Hormone Education member physicians have financial
ties to Wyeth. Medical professionals without ties to Wyeth called the course
materials "not good science" and "pure,
nine years ago, I was sick to my stomach from a bad migraine headache, so my
doctor prescribed the anti-nausea drug Phenergan®. But the giant drug
corporation Wyeth - the manufacturer of Phenergan® - did not warn my
doctors not to use the IV-push method of administering the drug, which can
cause gangrene and amputation. And Wyeth knew that at least 20 other
amputations had already occurred from administering Phenergan® in this
dangerous way. Because of Wyeth's negligence, I lost my arm. My life as a
professional musician changed forever.
A Vermont jury agreed that Wyeth
negligently caused my amputation and awarded me compensation. But Wyeth, the
entire drug industry, and the US Chamber of Commerce - with strong support from
the Bush administration - took my case to the
Supreme Court, saying that just because
the FDA approves drugs, people injured by those drugs should not be compensated
in our court system (a legal theory known as "pre-emption"). That argument made
no sense. The FDA is overworked and underfunded, and it
depends on the drug
companies themselves for information about problems with
medications." - Diana Levine
In Wyeth v. Levine the US
Supreme Court held that approval of a
medication by federal regulators does not shield the manufacturer from
liability under state law.
Zicam® 2006 Matrixx, the manufacturer of Zicam®, pays $12 million
to settle 340 lawsuits from Zicam® users who claimed that the product
destroyed their sense of smell, a condition known as anosmia. Hundreds more
such suits have since been filed. Reports of destroyed sense of smell started
"Two federal drug officials
have concluded that asthma sufferers
risk deathif they continue to use four hugely popular
asthma drugs - Advair®,
Symbicort®, Serevent® and Foradil®." - Gardiner Harris, December 5,
phenylpropanolamine and catastrophic
stroke 1982 FDA
report warns that phenylpropanolamine has "the ability to cause
effects, cerebral hemorrhage and cardiac arrhythmias."
later a memo from the medical services department at Sandoz
Pharmaceuticals, which made the phenylpropanolamine products Triaminic®
and Tavist-D®, referred to phenylpropanolamine as "an agent known to cause
hypertension and stroke," yet the
industry accelerated their marketing of phenylpropanolamine, winning
FDA approval to sell prescription phenylpropanolamine products on an
over-the-counter basis and even introducing flavorful new formulas for
consistently challenged any notion that phenylpropanolamine could be
dangerous and dismissed evidence to the
Tracy Patton, at 37, and
Tricia Newenham, at 15, had catastrophic strokes.
hours before the catastrophic
strokes each victim had taken an over-the-counter medicine containing
phenylpropanolamine the active ingredient in scores of popular nonprescription
decongestants and diet aids.
1999 Landmark $5
million Yale University study sponsored by the
concludes the use of phenylpropanolamine is associated with an increased risk
of catastrophic stroke. Tracy Patton and Tricia Newenham, who had taken
Triaminic® cold syrup, were among hundreds of phenylpropanolamine consumers
who had catastrophic strokes.
launches a yearlong campaign to keep the results quiet and stall
government regulation. By the time the phenylpropanolamine is removed from
over-the-counter medicine, 13 months and hundreds of strokes later, the
companies has reformulated their
brand names with
little interruption in sales or cash flow. The
pharmaceutical market for
phenylpropanolamine, estimated at $500 million to $1 billion anually, is saved
and in the interim, Americans continue to purchase phenylpropanolamine products
off the shelf assuming they were safe.
industry hoped to survive the 2000 cold
season without pulling phenylpropanolamine products. Early in November 2000 two
weeks after an FDA advisory panel concluded that phenylpropanolamine
could be hazardous, an official with
Bayer, which made Alka-Seltzer
Plus® with phenylpropanolamine, drafted a proposed "phenylpropanolamine
crisis action plan."
The crisis action plan's stated objectives: "Delay
mandatory implementation of FDA recommendation. Blunt PR impact by
highlighting as questionable study conclusions as they pertain to cough/cold
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