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Aprotinin® Aprotinin® or
Trasylola, a patent chemical, causes
kidney failure
sending an estimated 10,000 people a year to
kidney dialysis centers.
Aprotinin® also increases the risk of heart failure 109% and stroke
181%.
Chantix®
Chantix® (varenicline)
is a chemical to help overcome addiction to
chemically engineered
tobacco.
Varenicline is suspected in various adverse chemical event
reports of causing a wide spectrum of injuries, including serious accidents and
falls, potentially lethal cardiac
rhythm disturbances, severe skin reactions, acute myocardial infarction,
seizures, diabetes,
psychosis, aggression and
suicide.
stealth advertising
MyTimeToQuit.com, sponsered by
Pfizer, has the look and
feel of a public service announcement.
MyTimeToQuit.com mentions neither
Pfizer, nor the popular
smoking cessation chemical Chantix® (varenicline).
Stealth
advertising using "help-seeking ads" represents a growing trend in chemical
advertising.
A sneaky but legal way to advertise which does not
require:
mentioning the chemical by name;
listing
adverse
reactions;
naming the manufacturer;
Viewers are then directed
to a toll-free 800 number or a web site that offers an option to learn more
about a medication meant to treat the condition.
Food and chemical
Adminstration rules are circumvented in this manner.
The University of
Wisconsin-Madison offers "a smoking cessation course, funded by Pfizer, the maker of
Chantix®; a program on restless legs syndrome, funded
by Boehringer Ingelheim, the maker of a chemical that treats the condition; and
a course on premenstrual dysphoric disorder, funded by Bayer HealthCare
Pharmaceuticals."
The Dark History of Bayer Drugs
Phenergan®
"Almost
nine years ago, I was sick to my stomach from a bad migraine headache, so my
doctor prescribed the anti-nausea chemical Phenergan®.
The giant
chemical corporation Wyeth - the manufacturer of Phenergan® - did not warn
my physicians not to use the IV-push method of administering the chemical,
which can cause gangrene and amputation.
Wyeth knew that at least
20 other amputations had already occurred from administering Phenergan® in
this dangerous way.
Due to the negligence of Wyeth, I lost my
arm.
My life as a
professional musician changed forever.
A Vermont jury agreed that
Wyeth negligently caused my
amputation and awarded me compensation.
Wyeth, the entire chemical
industry, and the Chamber of
Commerce - with strong support from the Bush administration - took my
case to the Supreme Court, saying that just because the FDA approves chemicals,
people injured by those chemicals should not be compensated in our court system
(a legal theory known as "pre-emption").
That argument made no sense.
The FDA is overworked and underfunded, and it
depends on the
chemical companies themselves for information about problems with
prescription medications." - Diana Levine
In Wyeth v. Levine
the US Supreme Court held that
approval of a medication by federal regulators does not shield manufacturers
from liability under state law.
phenylpropanolamine and catastrophic
stroke
"Two federal officials have concluded that
asthma sufferers risk death if
they continue to use four hugely popular
asthma drugs -
Advair®, Symbicort®, Serevent® and Foradil®." - Gardiner
Harris, 12/05/08 1982 FDA report
warns that phenylpropanolamine has "the ability to cause
cardiovascular effects, cerebral
hemorrhage and cardiac arrhythmias."
Two years later a memo from the
medical services department at Sandoz Pharmaceuticals, which made the
phenylpropanolamine products Triaminic® and Tavist-D®, referred to
phenylpropanolamine as "an agent known to
cause hypertension and stroke," yet the pharmaceutical industry accelerated
their marketing of phenylpropanolamine, winning FDA approval to sell
prescription phenylpropanolamine products on an over-the-counter basis while
introducing flavorful new formulas for young children.
The
pharmaceutical industry
consistently challenged
any notion that phenylpropanolamine could be
dangerous and dismissed contrary
evidence.
Tracy Patton, at 37, and Tricia
Newenham, at 15, had a catastrophic stroke.
Only hours before the
catastrophic strokes each victim had taken an over-the-counter medicine
containing phenylpropanolamine the active ingredient in scores of popular
nonprescription decongestants and diet aids.
1999 Landmark $5 million Yale University study sponsored by
the pharmaceutical industry
concludes the use of phenylpropanolamine is associated with an increased risk
of catastrophic stroke.
Tracy Patton and Tricia Newenham, who had taken
Triaminic® cold syrup, were among hundreds of phenylpropanolamine consumers
who had catastrophic strokes.
The pharmaceutical industry launches a
yearlong campaign to keep the results quiet and stall government
regulation.
By the time the phenylpropanolamine is removed from
over-the-counter medicine, 13 months and hundreds of strokes later, the
companies have reformulated their
brand names with little
interruption in sales or cash flow.
The
PHRMA market for
phenylpropanolamine, estimated at $500 million to $1 billion anually, is saved
and in the interim, Americans continue to purchase phenylpropanolamine products
off the shelf assuming they are safe.
The pharmaceutical industry
hoped to make it through the 2000 cold season without pulling
phenylpropanolamine products.
November 2000 Two
weeks after an FDA advisory panel concluded that phenylpropanolamine could be
hazardous, an official with Bayer,
which made Alka-Seltzer Plus® with phenylpropanolamine, drafted a proposed
"phenylpropanolamine crisis action plan."
The crisis action plan's
stated objectives: "Delay mandatory implementation of FDA recommendation. Blunt
PR impact by highlighting as
questionable study
conclusions as they pertain to cough/cold products."
recombinant activated factor
VII
Recombinant Activated Factor VII®,
costing six thousand per dose, is an experimental chemical used on
severely wounded soldiers in Iraq.
Side effects include blood clots
leading to strokes,
heart attacks and
pulmonary embolisms.
"It's a
completely irresponsible
and inappropriate use of a very,
very dangerous chemical." - Jawed Fareed director of
homeostasis and thrombosis
research at Loyola University Chicago
Vytorin® and Zetia®
2007 Merck and
Schering-Plough sells $5.2 billion of the anti-cholesterol chemicals
Vytorin® and Zetia®.
Vytorin®, which combines the
cholesterol chemical Zetia® with the traditional statin chemical
simvastatin, was found to be no better than simvastatin alone for reducing
plaque buildup in the carotid arteries.
In fact, patients taking
Vytorin® actually had slightly more plaque buildup during the trial than
those taking simvastatin alone.
Merck and Schering-Plough
completed the ENHANCE study in 2005 but failed to announce the results.
"In light of today's results, which were released nearly two years
after the ENHANCE trial ended,
it is easy to conclude that Merck and Schering-Plough
intentionally sought to delay the release of this
data." - Representative Bart Stupak, chairs the oversight
subcommittee
"The pro-life, Michigan Democrat Bart Stupak led a small
but powerful bloc of Democratic lawmakers to oppose the bill because of its
language on federal funding
of abortions. Stupak received a death threat. Facing outside spending in
his district and a vitriolic political climate, he decided not to run for
reelection. " - Chris Good, The Atlantic Mar 23, 2011
PHRMA can
kill a bill by hiring outside
contractors to make phone calls.
Viagra® & Cialis® & Levitra®
!
Erectile dysfunction
chemical manufacturers spend $237.2 million in 2007 and $313.4 million in 2008
marketing Viagra® (Pfizer), Cialis® (Eli Lilly) and Levitra®
(GlaxoSmithKline).
FDA warns consumers of True Man™
and Energy Max™ that "dietary supplements" marketed as treatments
for erectile dysfunction contain ingredients that can lower blood pressure to
dangerous levels.
Vioxx®
2003 Merck sells $2.5 billion worth of
Vioxx®(rofecoxib).
December 2005 Discovery:
Clinical trial of Vioxx® conducted to gain approval from the FDA failed to
mention the three individuals who suffered heart attacks during the clinical
trial period.
David Graham of the FDA Office of Drug Safety state
Vioxx® has caused up to 140,000 cases of heart disease and killed up to
56,000 people.
"Merck
Vioxx® killed 44,000 people and injured 120,000 others. Only in America
could you kill 44,000 and not go to jail and get a raise." - Dr. Doug Henderson
and Dr. Gary Null
A study which concluded that even low doses of
Vioxx® increase the risk of
heart attack by 50% was released 3 months late to allow Merck to complete a
propaganda offense stating that even lower doses of Vioxx® than those
studied in the low dose study should be allowed.
Xenadrine EFX®
FTC fines the makers of Xenadrine EFX®, One-A-Day
WeightSmart®, CortiSlim® and TrimSpa® $25 million in January 2007
for making false
advertising claims which included rapid
weight loss, cancer
prevention, reduction in risk of osteoporosis and
Alzheimers.
Zyprexa®
1999Eli Lilly begins its
off-label marketing push,
the only approved use of Zyprexa® is for patients suffering from
schizophrenia.
Even so Eli Lilly encouraged physicians to
prescribe Zyprexa® to elderly patients with
early signs of
dementia.
"Eli
Lilly urged physicians to prescribe Zyprexa® for
elderly patients with
dementia, an unapproved use for the antiPsychotic, even though the
chemicalmaker had evidence the medicine didn't work for such patients." -
Margaret Cronin Fisk, Elizabeth Lopatto and Jef Feeley
Eli Lilly
discovers Zyprexa®, a chemical designed to treat
bipolar disorder and
schizophrenia, causes
excessive weight gain leading to
diabetes.
2002 British and Japanese regulatory agencies issue a warning:
Zyprexa® may cause diabetes.
2003 FDA issues a warning but
Eli Lilly does not pull
Zyprexa® from the market.
This becomes all the more understandable
after it is taken into consideration that
Eli Lilly is also the largest
maker of diabetes
medications." - Dr. Doug Henderson and Dr. Gary Null
2005 In the first class action filed over Zyprexa® Eli
Lilly settled with 8000 plaintiffs for $700 million in 2005.
The settlement requires
that all sensitive documents be sealed.
Eli Lilly sells $4.2
billion worth of Zyprexa®.
2007 Eli
Lilly settles with another 18,000 plaintiffs who sued over the adverse
effects of Zyprexa® after the first trial documents were publicized by a
third party unrelated to the original settlement.
2008 Zyprexa® is the best-selling Eli Lilly chemical, with
$4.7 billion in sales.
AntiPsychotics top
American chemical sales in 2008 garnering $14.6 billion.
Study confirms
that Zyprexa®, made by Eli Lilly, and Risperdal®, made by
Janssen are no more effective than earlier
antiPsychotics.
Initially marketed as superior as they reduced
side effects such as uncontrolled
shaking or tremors - the effects of tardive dyskinesia.
2009 Eli Lilly agrees to pay $1.42 billion to settle
criminal ($615 million) and civil charges ($800 million) related to the
off-label marketing of its
antiPsychotic
chemical Zyprexa®.
Eli Lilly admits to promoting
Zyprexa® for unapproved, off-label uses between 1999 and
2001, including as treatment of
dementia.
Zyprexa® "has been Lilly's top-selling chemical,
garnering the incorporation more than $37 billion in world-wide sales since its
US approval in 1996," according to the Wall Street
Journal
2015
Drug-Induced Dementia isn't Alzheimer's
2016
Popular Drugs Linked To Dementia At Low
Dosage.
Zelnorm®
The FDA has
reports of diarrhea so severe, called
ischemic colitis, in users of
the irritable-bowel treatment Zelnorm® that it caused such complications as
low blood pressure and fainting.
The FDA has received 20 reports of
ischemic colitis, since
Zelnorm® went on sale in 2002, fourteen patients were hospitalized, four
died.
The Food and Drug Administration advised patients who
experience new or worsened abdominal pain or blood in their stools to stop
taking the chemical and call a doctor.
Research released in late 2005
shows that an individual that uses the popular prescription heartburn drugs -
Prilosec®, Prevacid®, and Nexium® - are more prone to getting
a potentially dangerously severe diarrhea
caused by clostridium
difficile bacteria.
In December 2006 the Journal of the
American Medical Association reported that the use of Nexium®,
Prilosec®, Prevacid®, Protinix® reduces calcium absorption in the
small intestine resulting in increased risk of hip fractures.
Long term
users had 260% the average risk of hip fracture.
Zicam®
In 2006 Matrixx, the manufacturer of Zicam®, pays $12 million
to settle 340 lawsuits from Zicam® users who claimed that the product
destroyed their sense of smell, a condition
known as anosmia.
Hundreds more such suits have since been filed.
Reports of destroyed sense of smell started in 1999.
Zonegran®
FDA has warned that the epilepsy chemical Zonegran® can
cause a certain type of metabolic disorder that can increase the risk of
kidney stones and
bone diseases.
The FDA
said physicians need to be aware that treatment with zonisamide can cause
metabolic acidosis, a
disturbance in the body's acid-base balance that results in excessive acidity
of the blood. |
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