Aprotinin®

Aprotinin® or Trasylola, a patent chemical, causes kidney failure sending an estimated 10,000 people a year to kidney dialysis centers.

Aprotinin® also increases the risk of heart failure 109% and stroke 181%.

Chantix®

Pfizer's quit-smoking Chantix fails study in adolescent smokers

Chantix® (varenicline) is a chemical to help overcome addiction to chemically engineered tobacco.

Varenicline is suspected in various adverse chemical event reports of causing a wide spectrum of injuries, including serious accidents and falls, potentially lethal cardiac rhythm disturbances, severe skin reactions, acute myocardial infarction, seizures, diabetes, psychosis, aggression and suicide.

stealth advertising

MyTimeToQuit.com, sponsered by Pfizer, has the look and feel of a public service announcement.

MyTimeToQuit.com mentions neither Pfizer, nor the popular smoking cessation chemical Chantix® (varenicline).

Stealth advertising using "help-seeking ads" represents a growing trend in chemical advertising.

A sneaky but legal way to advertise which does not require:

mentioning the chemical by name;

listing adverse reactions;

naming the manufacturer;

Viewers are then directed to a toll-free 800 number or a web site that offers an option to learn more about a medication meant to treat the condition.

Food and chemical Adminstration rules are circumvented in this manner.

The University of Wisconsin-Madison offers "a smoking cessation course, funded by Pfizer, the maker of Chantix®; a program on restless legs syndrome, funded by Boehringer Ingelheim, the maker of a chemical that treats the condition; and a course on premenstrual dysphoric disorder, funded by Bayer HealthCare Pharmaceuticals."

The Dark History of Bayer Drugs

Phenergan®

"Almost nine years ago, I was sick to my stomach from a bad migraine headache, so my doctor prescribed the anti-nausea chemical Phenergan®.

The giant chemical corporation Wyeth - the manufacturer of Phenergan® - did not warn my physicians not to use the IV-push method of administering the chemical, which can cause gangrene and amputation.

Wyeth knew that at least 20 other amputations had already occurred from administering Phenergan® in this dangerous way.

Due to the negligence of Wyeth, I lost my arm.

My life as a professional musician changed forever.

A Vermont jury agreed that Wyeth negligently caused my amputation and awarded me compensation.

Wyeth, the entire chemical industry, and the Chamber of Commerce - with strong support from the Bush administration - took my case to the Supreme Court, saying that just because the FDA approves chemicals, people injured by those chemicals should not be compensated in our court system (a legal theory known as "pre-emption").

That argument made no sense. The FDA is overworked and underfunded, and it depends on the chemical companies themselves for information about problems with prescription medications." - Diana Levine

In Wyeth v. Levine the US Supreme Court held that approval of a medication by federal regulators does not shield manufacturers from liability under state law.

recombinant activated factor VII

Recombinant Activated Factor VII®, costing six thousand per dose, is an experimental chemical used on severely wounded soldiers in Iraq.

Side effects include blood clots leading to strokes, heart attacks and pulmonary embolisms.

"It's a completely irresponsible and inappropriate use of a very, very dangerous chemical." - Jawed Fareed director of homeostasis and thrombosis research at Loyola University Chicago

Vytorin® and Zetia®

2007 Merck and Schering-Plough sells $5.2 billion of the anti-cholesterol chemicals Vytorin® and Zetia®.

Vytorin®, which combines the anti-cholesterol chemical Zetia® with the traditional statin chemical simvastatin, was found to be no better than simvastatin alone for reducing plaque buildup in the carotid arteries.

In fact, patients taking Vytorin® actually had slightly more plaque buildup during the trial than those taking simvastatin alone.

Merck and Schering-Plough completed the ENHANCE study in 2005 but failed to announce the results.

"In light of today's results, which were released nearly two years after the ENHANCE trial ended, it is easy to conclude that Merck and Schering-Plough intentionally sought to delay the release of this data." - Representative Bart Stupak, chairs the oversight subcommittee

"The pro-life, Michigan Democrat Bart Stupak led a small but powerful bloc of Democratic lawmakers to oppose the bill because of its language on federal funding of abortions. Stupak received a death threat. Facing outside spending in his district and a vitriolic political climate, he decided not to run for reelection. " - Chris Good, The Atlantic Mar 23, 2011

PHRMA can kill a bill by hiring outside contractors to make phone calls.

Viagra® & Cialis® & Levitra® !

Erectile dysfunction chemical manufacturers spend $237.2 million in 2007 and $313.4 million in 2008 marketing Viagra® (Pfizer), Cialis® (Eli Lilly) and Levitra® (GlaxoSmithKline).

FDA warns consumers of True Man™ and Energy Max™ that "dietary supplements" marketed as treatments for erectile dysfunction contain ingredients that can lower blood pressure to dangerous levels.

Vioxx®

2003 Merck sells $2.5 billion worth of Vioxx®(rofecoxib).

December 2005 Discovery: Clinical trial of Vioxx® conducted to gain approval from the FDA failed to mention the three individuals who suffered heart attacks during the clinical trial period.

David Graham of the FDA Office of Drug Safety state Vioxx® has caused up to 140,000 cases of heart disease and killed up to 56,000 people.

"Merck Vioxx® killed 44,000 people and injured 120,000 others. Only in America could you kill 44,000 and not go to jail and get a raise." - Dr. Doug Henderson and Dr. Gary Null

A study which concluded that even low doses of Vioxx® increase the risk of heart attack by 50% was released 3 months late to allow Merck to complete a propaganda offense stating that even lower doses of Vioxx® than those studied in the low dose study should be allowed.

Xenadrine EFX®

FTC fines the makers of Xenadrine EFX®, One-A-Day WeightSmart®, CortiSlim® and TrimSpa® $25 million in January 2007 for making false advertising claims which included rapid weight loss, cancer prevention, reduction in risk of osteoporosis and Alzheimer's.

Zyprexa®

1999Eli Lilly begins its off-label marketing push, the only approved use of Zyprexa® is for patients suffering from schizophrenia.

Even so Eli Lilly encouraged physicians to prescribe Zyprexa® to elderly patients with early signs of dementia.

"Eli Lilly urged physicians to prescribe Zyprexa® for elderly patients with dementia, an unapproved use for the antiPsychotic, even though the chemicalmaker had evidence the medicine didn't work for such patients." - Margaret Cronin Fisk, Elizabeth Lopatto and Jef Feeley

Eli Lilly discovers Zyprexa®, a chemical designed to treat bipolar disorder and schizophrenia, causes excessive weight gain leading to diabetes.

2002 British and Japanese regulatory agencies issue a warning: Zyprexa® may cause diabetes.

2003 FDA issues a warning but Eli Lilly does not pull Zyprexa® from the market.

This becomes all the more understandable after it is taken into consideration that Eli Lilly is also the largest maker of diabetes medications." - Dr. Doug Henderson and Dr. Gary Null

2005 In the first class action filed over Zyprexa® Eli Lilly settled with 8000 plaintiffs for $700 million in 2005.

The settlement requires that all sensitive documents be sealed.

Eli Lilly sells $4.2 billion worth of Zyprexa®.

2007 Eli Lilly settles with another 18,000 plaintiffs who sued over the adverse effects of Zyprexa® after the first trial documents were publicized by a third party unrelated to the original settlement.

2008 Zyprexa® is the best-selling Eli Lilly chemical, with $4.7 billion in sales.

AntiPsychotics top American chemical sales in 2008 garnering $14.6 billion.

Study confirms that Zyprexa®, made by Eli Lilly, and Risperdal®, made by Janssen are no more effective than earlier antiPsychotics.

Initially marketed as superior as they reduced side effects such as uncontrolled shaking or tremors - the effects of tardive dyskinesia.

2009 Eli Lilly agrees to pay $1.42 billion to settle criminal ($615 million) and civil charges ($800 million) related to the off-label marketing of its antiPsychotic chemical Zyprexa®.

Eli Lilly admits to promoting Zyprexa® for unapproved, off-label uses between 1999 and 2001, including as treatment of dementia.

Zyprexa® "has been Lilly's top-selling chemical, garnering the incorporation more than $37 billion in world-wide sales since its US approval in 1996," according to the Wall Street Journal

2015 Drug-Induced Dementia isn't Alzheimer's

2016 Popular Drugs Linked To Dementia At Low Dosage.

Zelnorm®

Analysis of 59,824 hospitalizations

The FDA has reports of diarrhea so severe, called ischemic colitis, in users of the irritable-bowel treatment Zelnorm® that it caused such complications as low blood pressure and fainting.

The FDA has received 20 reports of ischemic colitis, since Zelnorm® went on sale in 2002, fourteen patients were hospitalized, four died.

The Food and Drug Administration advised patients who experience new or worsened abdominal pain or blood in their stools to stop taking the chemical and call a doctor.

Research released in late 2005 shows that an individual that uses the popular prescription heartburn drugs - Prilosec®, Prevacid®, and Nexium® - are more prone to getting a potentially dangerously severe diarrhea caused by clostridium difficile bacteria.

In December 2006 the Journal of the American Medical Association reported that the use of Nexium®, Prilosec®, Prevacid®, Protinix® reduces calcium absorption in the small intestine resulting in increased risk of hip fractures.

Long term users had 260% the average risk of hip fracture.

Zicam®

In 2006 Matrixx, the manufacturer of Zicam®, pays $12 million to settle 340 lawsuits from Zicam® users who claimed that the product destroyed their sense of smell, a condition known as anosmia.

Hundreds more such suits have since been filed.

Reports of destroyed sense of smell started in 1999.

Zonegran®

FDA has warned that the epilepsy chemical Zonegran® can cause a certain type of metabolic disorder that can increase the risk of kidney stones and bone diseases.

The FDA said physicians need to be aware that treatment with zonisamide can cause metabolic acidosis, a disturbance in the body's acid-base balance that results in excessive acidity of the blood.

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