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adjuvant
Several substances other than antigens
are included in vaccines.
These include stabilizers, preservatives,
buffers, antibiotics and adjuvants.
Stabilizers are used to maintain
effectiveness during storage.
Preservatives are used to prevent
bacterial or fungal contamination.
Buffers, such as monopotassium
phosphate, serve to resist changes in pH.
COVAX
Humanitarian Buffer Explained
"COVAX was designed to ensure the most
vulnerable in every country get access to COVID-19 vaccines.
What about
people in conflict zones or humanitarian settings that cant be reached by
government vaccination
campaigns?
Gavi approved a Humanitarian Buffer to
ensure no one is left behind."
Ionic compounds adjust tonicity and
maintain osmolarity.
Some of these substances, for example gelatin and
thimerosal, have been removed from vaccines because of their undesirable side
effects.
1928 Staphylococcus
infection kills 12 of 21 children inoculated with a diphtheria vaccine that
lacked a preservative.
Preservatives available bur not standardly used
in this period of time include thimerosal,
phenoxyethanol,
and formaldehyde.
Phenoxyethanol,
a glycol ether, is
toxic to the kidneys,
nervous system, and
liver, and repeated, long-term
exposure can cause organ damage.
Phenoxyethanol is synthesized by
treating phenol with
ethylene oxide in an alkaline medium.
Phenoxyethanol along with
parabens; sulfates; phthalates;
polyethylene;
propylene glycol
and butylene
glycol in comestics should be avoided.
The Japan and EU consider
phenoxyethanol safe for use as a preservative with a maximum concentration of
1.0%.
FDA issued a public warning
revealing that the ingestion of phenoxyethanol can be toxic and harmful for
infants when it was found in a nipple cream called Mommy's
Bliss.
Aluminium in brain tissue in autism
Neurodevelopmental disorders: thimerosal
immunizations
'ASIA' -
autoimmune/inflammatory syndrome induced by adjuvants
1960s Refined peanut oil is widely adopted as an excipient of
choice in the production of vaccines.
squalene
"Human oil adjuvants are the most insidious
chemical weapon ever devised. Squalene is a trigger for a real
biological weapon - what Soviet
observers called a
biological time bomb." - Gary MatsumotoSqualene, an oil
molecule native to the human body, is found throughout the
nervous system and the
brain.
Squalene is also the biochemical precursor to the whole
family of steroids.
Squalene adjuvants are key ingredients in the next
generation of vaccines intended for mass immunization around the globe.
Squalene galvanizes the
immune system into
attacking the nervous
system.
1970s Michael Whitehouse and
Frances Beck inject squalene oil combined with other materials into rats and
find that few oils are more effective at causing the animal versions of
arthritis and
multiple sclerosis.
There is a close match between the squalene-induced diseases in animals
and those observed in humans injected with this oil:
rheumatoid arthritis,
multiple sclerosis and
systemic lupus erythematosus.
Cannabinoids inhibit neurodegeneration in models of multiple
sclerosis
Clinical Use of Cannabinoids for Symptom Control in Multiple
Sclerosis
Changes Uncovered in Gut Bacteria of People with Multiple
Sclerosis
Digesting squalene isn't a problem.
Injecting
squalene into the blood galvanizes the
immune system to
attack.
Autoimmune disorders
occur when the body identifies
molecules as having breached system barriers - they are
out-of-place.
Once the body identifies molecules as an enemy a
self-destructive cross reaction may take place against the same molecule where
it occurs naturally in the body - where it is critical to the health of the
nervous
system.
Once self-destruction begins, it
doesn't stop as the body keeps making the molecule that
the immune system is trained to
attack and destroy.
By
distorting the
configuration of the native protein, the immune system attacks its own antigens,
resulting in an autoimmune or
allergic
response.
"There are now data in more than two dozen peer-reviewed
scientific papers, from ten different laboratories in the US, Europe,
Asia and
Australia, documenting that
squalene-based adjuvants can induce
autoimmune
disorders in animals - observed in mice, rats, guinea pigs and
rabbits.
Sweden's
Karolinska Institute has demonstrated that squalene alone can induce the
animal version of rheumatoid
arthritis.
The Polish Academy of Sciences has shown that in
animals, squalene alone can produce catastrophic injury to the
nervous system and the
brain.
The University of Florida Medical School has shown
that in animals, squalene alone can
induce production of
antibodies specifically associated with systemic lupus erythematosus." - Dr. Johnny
Lorentzen, Karolinska Institute Sweden
"Squalene contributed to the cascade of reactions
called "Gulf War syndrome" -
arthritis,
fibromyalgia,
lymphadenopathy,
rashes, photosensitive
rashes, malar rashes,
chronic fatigue,
chronic headaches,
abnormal body hair loss,
non-healing skin
lesions, aphthous ulcers, dizziness,
weakness,
memory loss,
seizures,
mood changes,
neuropsychiatric
problems, thyroid
malfunction, anemia,
elevated ESR (erythrocyte sedimentation rate),
systemic lupus erythematosus,
multiple sclerosis,
Lou Gehrig's disease,
Raynaud's phenomenon,
Sjörgren's
syndrome, chronic
diarrhea, night sweats and low-grade fever." -
micropaleontologist Dr. Viera Scheibner
"The tomatoes were
peeled by hand and only the peels were
analyzed."
Biological Function of the Prion Protein
The prion
glycoprotein, PrPC, is located at the cell surface, tethered to the
plasma membrane through a glycosyl-phosphatydil inositol
anchor.
Misfolding of PrPC is associated with the
transmissible spongiform encephalopathies), whereas its normal conformer serves
as a receptor for oligomers of the ß-amyloid peptide; pathogenesis of
Alzheimers disease.
2000 David Ronald Brown
advanced research related to the role of metals in the cause of prion diseases
such as vCJD.
Media
attention focused on this work when it became associated with that of the
farmer Mark Purdey, who argued that human cases of vCJD might be caused by
exposure to the systemic organophosphate insecticide Phosmet, used as a dip to
contain warble fly, and manganese in the salt lick.
"Many might be
surprised to hear that organophosphates were developed by Nazi chemists during
the course World War Two, as a chemical weapon nerve agent.
One
formulation of the insecticide - Maneb, or Mancozeb - actually contains
manganese in addition to organophosphate.
Phosmet organophosphate has
been used at high doses in British warble fly campaigns.
In 1996, ICI
subsidiary Zeneca sold the phosmet patent to a PO Box company in Arizona called
Gowan -just one week before the UK government admitted to a link between BSE
and nvCJD.
The politically well-connected British pharmaceuticals
group, ICI has the financial and political clout to block research into any
cause other than the infective model.
Indeed
no substantive alternative
research has been done.
British BSE disease management and research
bodies have taken decisions that do not seem guided by spirited scientific
enquiry.
Mysterious prions that jump species is a preferred research
arena.
Scientist and organic farmer, Mark Purdey gave evidence to the
UK BSE inquiry, that warble fly insecticide was the cause of the disease.
The scientist wheeled out to rubbish Purdy's evidence - Dr. David Ray,
later turned out to have been receiving funding from the insecticide
manufacturer ICI.
A lobby group that includes Bayer, Monsanto,
Novartis, Pfizer,
Roche and Schering-Plough was behind the effort to discredit Purdey.
In
December 1999, the same David Ray was appointed to the UK Veterinary Products
Committee (VPC) -a government body that licences animal medicines." - Fintan
Dunne
Organophosphate can deform
the prion protein, rendering it ineffective at buffering free radicals.
These prion are then partial bond with manganese and become 'rogue'
prion.
A
chain reaction where by
rogue prions turn others to rogues explains the bovine spongiform disease
mechanism.
Brown showed how prion protein bonds benignly with copper,
but lethally with manganese.
Even natural variations in relative environmental
availability of manganese versus copper can trigger prion degradation.
Consequences
of manganese replacement of copper for prion protein function and proteinase
resistance
Cannabis Kills MRSA, Disrupts Prion Diseases
COVID-19 RNA Based Vaccines and the Risk of Prion
Disease
2009
"Some adjuvants may exert adverse effects upon
injection or, on the other hand, may not trigger a full immunological
reaction.
The mechanisms underlying adjuvant
adverse reactions are
under renewed scrutiny because of the enormous implications for vaccine
development.
The ability of the immune system to recognize molecules that
are broadly shared by pathogens is, in part, due to the presence of special
immune receptors called toll-like receptors (TLRs) that are expressed on
leukocyte membranes.
The very fact that TLR activation leads to
adaptive immune responses to foreign entities explains why so many adjuvants
used today in vaccinations are developed to mimic TLR ligands." - Adjuvants and autoimmunity
2015 "Since vaccines are given to previously
healthy hosts, who may have never developed the disease had they not been
immunized, adverse
reactions should be carefully accessed and evaluated even if they represent
a limited number of occurrences." - Vaccines, adjuvants and autoimmunity
2016 "A
previously healthy 36-year-old female presented with
clinical symptoms of
thyrotoxicosis including
tachycardia,
anxiety, and
tenderness in her neck .
One month before her presentation, she received
H1N1 vaccine.
Thyroid function tests
confirmed remarkable thyrotoxicosis." -
Autoimmune Disorder Induced by Adjuvants and Thyroid
Autoimmunity
2017 "Autoimmune disorder induced by adjuvants
(ASIA) has been widely described in many studies conducted thus far." - Autoimmune
disorder induced by adjuvants
March 27, 2018 "Incidence of autoimmune
disorder has been rising at an enormous rate.
A study indicates
that a significant factor in causing them may be the common bakers or brewers
yeast, Sacccharomyces cerevisiae used in many vaccinations, including
HepB, which is given to nearly all newborn babies in the United States before
they're a day old.
The specific part of S. cerevisiae that's of
concern is mannan, which is found in the cell walls of yeasts and also in
mammalian glycoproteins.
Glycoprotein is found in cell
walls, connective tissues like
collagen,
gastrointestinal mucous
secretions, and blood plasma.
Glycoproteins perform
many functions.
Obviously, if the
immune system goes on
the attack against mannan or polysaccharide, it can be devastating.
Yet, that appears to be
happening in many autoimmune diseases." -
Heidi Stevenson, Yeast in Vaccines Tied to Autoimmune
Diseases
Glycoproteins contain oligosaccharide chains covalently
attached to amino acid side-chains.
The
carbohydrate is attached
to the protein in a cotranslational or posttranslational modification.
This process is known as glycosylation.
Secreted extracellular
proteins are often glycosylated.
Anti-Saccharomyces cerevisiae antibodies in inflammatory bowel
disease
Anti-Saccharomyces as a Biomarker in Children With Crohn Disease
Prevalence anti-saccharomyces cerevisiae in primary
Sjögren's syndrome
Anti-Saccharomyces cerevisiae with Anti-ß2 Glycoprotein I
antibodies
Anti-Saccharomyces cerevisiae as antibodies in autoimmune
hepatitis
"There is an urgent need to start adequately adjusted
epidemiological studies to obtain better evidence which percentage of patients
develop symptoms of autoimmune disorders after
implant surgery." - ASIA;
Shoenfeld's syndrome: A new flame.
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